Persistent Arthralgia Associated with Chikungunya Virus Outbreak, US Virgin Islands, December 2014–February 2016

Leora R. Feldstein, Ali Rowhani-Rahbar, J. Erin Staples, Marcia R. Weaver, M. Elizabeth Halloran, and Esther M. Ellis

Emerging Infectious Diseases

April, 2017


After the 2014–2015 outbreak of chikungunya virus in the US Virgin Islands, we compared the prevalence of persistent arthralgia among case-patients and controls. Prevalence was higher in case-patients than controls 6 and 12 months after disease onset. Continued vaccine research to prevent acute illness and long-term sequelae is essential.