Preliminary assessment of the International Spreading Risk Associated with the 2019 novel Coronavirus (2019-nCoV) outbreak in Wuhan City

Matteo Chinazzi, Jessica T. Davis, Corrado Gioannini, Maria Litvinova, Ana Pastore y Piontti, Luca Rossi, Xinyue Xiong, M. Elizabeth Halloran, Ira M. Longini Jr., Alessandro Vespignani

MOBS Lab 2019 nCOV website

January 17, 2020

View PDF

ABSTRACT

Starting in December 2019, Chinese health authorities have been closely monitoring a cluster of pneumonia cases in the city of Wuhan, in Hubei Province. It has been determined that the pathogen causing the viral pneumonia among affected individuals is a new coronavirus (2019-nCoV)(1). As of January 17, 2020, 45 cases have been detected and confirmed in the region(2) with 3 additional cases detected and confirmed in Japan and Thailand(3; 4). The source of the outbreak is still unknown, however investigations have identified environmental samples that tested positive for 2019-nCoV at the Huanan Seafood Wholesale Market in Wuhan city. Some of the most recent cases did not report exposure to animal markets, thus suggesting that human-to-human transmission, although limited, is possible. Considering the potential international threat that an outbreak of a novel virus like this one poses to the world, in this report we provide a modeling analysis of the risk of dissemination of 2019- nCoV infections. By using the cases detected outside China, we also provide estimates of the potential outbreak size in Wuhan as of January 17th, 2020.